Fetal Bovine Serum(FBS) has been long used as a supplement for tissue culture media, supplying
growth factors and attachment factors essential for the culturing and proliferation of cells in vitro.
Although the major constitutes of serum are known such as albumin and tranferrin, some of the
minor components and their effect on cell growth have not been fully determined. These minor
components include nutrients such as amino acids, nucleotides, sugars, growth factors, hormons,
minerals, and lipids.
FBS is commercially avaliable from many manufacturers, and because cells grown in vitro are highly
sensitive, researchers usually tests specific batches to check for suitability for their specific cell type.
When changing from batch to batch it is usual to adapt the cells to the new batch of material, for
example, by mixig 50% of the old serum with 50% of the new serum and allowing the cells to
acclimatize to the new material.
Also downstream purification is the leading disadvantage to using FBS in cell culture media. For
example, monoclonal antibody production and recombinant protein secretion both require
purification to remove serum-derived gamma-globulin from the media.
Ceraplex is the most innovative cell culture supplement including several components, and is intended
to provide high performance and cost-effective option for researchers without changing any current
cell culture system. Researchers can reduce FBS up to 1.5% - 3% for the growth and maintenance of
a broad spectrum of established cell lines with Ceraplex added to culture media. This advantage
dramatically gives researchers to minimize FBS's batch-to-batch variation which could result in change
cell growth pattern and morphology.
Another advantage of Ceraplex is that researchers can make Serum-Free basal media using Ceraplex
without changing any culture environments. Simply add Ceraplex to the current culture media without
FBS. This will replace many of specialized expensive Serum-Free media.
No change in your culture system
Keep using your media,FBS and reagents with higher cell growth performance
Just add Ceraplex to your media with reduced FBS for cell maintenance
Minimizing FBS lot-to-lot variation
Simply reduce your FBS requirement up to 1-3%, minimize FBS lot-to-lot variation
Providing better performance without cell morphology change caused by FBS
Significantly reduces cost by reducing % of FBS required for optimal growth
10% FBS can be reduced to as little as 1.5-3%
Optimized for broad spectrum
Works well for broad cell lines without changing current cell culture reagents
CHO, HT29, Hybridoma,Fibroblast, Vero, MDCK, HEK293, Hamster Kidney
Keratinocyte, Osteoblast, Red blood, Liver, Cadiac, Neural and etc..
Optimal performance in serum-free
Providing better performance with your current culture media for serum-free culture
Add Ceraplex to your media and culture without serum